• LustyArgonian@lemmy.world
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    2 days ago

    In a recent post, I tried to introduce a conceptual tool which I (as humorously and self-deprecatingly as possible) named after myself. In brief, “The Kory Scale” (TKS) is based on the hypothesis that the more a new or existing medical therapy is attacked in a coordinated, sustained fashion by the medical establishment and media, the more likely the treatment is both highly effective and safe.

    Okay, starting off with a made up fallacy is always a bad sign in science FYI… And so is going off that bad fallacy with more fallacies for 10 paragraphs.

    Before I go further, I just want to celebrate that “there is a new Sheriff in town,” given my friend and colleague RFK Jr. is now the Secretary of Health and Human Services

    LOL of course, that actually is pretty consistent w your pyramid conspiracies

    Although I am not a criminologist, my understanding from movies and news reports

    LOL

    Let me just say straight off that I know little about anti-neoplaston therapy outside of what I learned in the documentary

    LOL

    The exact incidence and magnitude of effectiveness is thus unknown to me but I argue that based on its score on TKS

    Please note that “TKS” is a made up thing by the writer, where if the scientific community doesnt like it, then it’s real/better by the ampunt they dislike it. It’s literally a vulnerable narcissist’s main thinking error. This is a vulnerable narcissist.

    Let’s just move on to the claims you’re making:

    https://en.m.wikipedia.org/wiki/Burzynski_Clinic

    The compounds are not licensed as drugs but are instead sold and administered as part of clinical trials at the Burzynski Clinic and the Burzynski Research Institute.

    Burzynski has since produced the compounds synthetically.

    The Burzynski Clinic is a clinic selling an unproven cancer treatment, which has been characterized as harmful quackery.[1] It was founded in 1976 and is located in Houston, Texas, in the United States. It offers a form of chemotherapy originally called “antineoplaston therapy” devised by the clinic’s founder Stanislaw Burzynski in the 1970s. Antineoplaston is Burzynski’s term for a group of urine-derived peptides, peptide derivatives, and mixtures. There is no accepted scientific evidence of benefit from antineoplaston combinations for various diseases, and the Clinic’s claimed successes have not been replicated by independent researchers.

    The clinic has been the focus of criticism primarily due to the way its antineoplaston therapy is promoted, the costs for people with cancer participating in trials of antineoplastons and problems with the way these trials are run. Legal cases have been brought as a result of the sale of the therapy without regulatory approval.

    Burzynski is also the president and founder of a pharmaceutical company, the Burzynski Research Institute, which manufactures his antineoplaston drugs.

    See the last line? Now tell me, how is he not ALSO PART of the Turf war your article is talking about?

    Reviewers of his scientific papers have disputed the design of the trials and scientific validity of the published results.[12][13][14]

    In February 2017, following lengthy hearings, the Texas Medical Board recommended Burzynski’s medical license be revoked, with the revocation suspended,[clarification needed] and a fine of $360,000 for billing irregularities and other violations.

    So it’s not just Wikipedia against him, but also medical boards. SO again, no issue with Wikipedia here, or science, he just is grifting people and you dont get what science even is (hint: it’s reproducible results).

    From A-10, antineoplaston AS2-1 was derived – a 4:1 mixture of phenylacetic acid and phenylacetylglutamine.[25] The Burzynski Clinic website states that the active ingredient of antineoplaston A10-I is phenylacetylglutamine

    So we know what it is, and it can indeed be synthesized (how else would the body make it, lol). We also already have people taking grains of thyroid, ovaries, adrenal glands, testes - and those organs are also used to make pharmaceuticals. Nothing stopping people from drinking pee or eating medically relevant foods.

    Further, you don’t always need a placebo for studies, you need a CONTROL group. Often the control group is given a placebo, but in this case, they could use other chemotherapy treatment as a control. They dont want to be more legitimate though, because their patients’ and their families would have better standing to sue them for lying/false advertising/snake oil. So no, it wasnt rejected for not having a placebo group and being too ethical to give cancer patients a placebo LOL

    From 1991 to 1995, the NCI initiated multiple phase II trials of antineoplastons. In 1995, after over $1 million had been spent on these trials, they were stopped due to fundamental conflicts between NCI investigators and Burzynski and his employees, notably around Burzynski’s insistence on approving all protocols in the NCI trial.

    The largest trial Burzynski registered was called CAN-1 and aimed to cover all clinic patients at that time. Jaffe wrote that CAN-1 was “a joke” of a clinical trial and explained the legal maneuvering:

    The CAN-1 protocol had almost two hundred patients in it and there were at least a dozen different types of cancers being treated. And since all the patients were already on treatment, there could not be any possibility of meaningful data coming out of the so-called clinical trial. It was all an artifice, a vehicle we and the FDA created to legally give the patients Burzynski’s treatment. The FDA wanted all of Burzynski’s patients to be on an IND [Investigational New Drug (IND) Application], so that’s what we did.

    The consensus among the professional community, as represented by the American Cancer Society[33] and Cancer Research UK[34] is that antineoplaston therapy is unproven, and the overall probability of the treatment turning out to be as claimed is low due to lack of credible mechanisms and the poor state of research after more than 35 years of investigation. Antineoplaston treatments have significant known side effects including severe neurotoxicity. Hypernatremia is also a significant risk given the high levels of sodium in antineoplaston infusions.

    Gee, I dont think Wikipedia is the issue lol my word

    The real cancer conspiracy is that corporations wont let us have Medicaid for All. That would detect cancer (and toxins) and allow us to class action sue companies for them. Cant sue if it was never detected. Thats why they find carcinogens and lead in kids’ products so much - their products dont have more lead in them, but kids all can be on Medicaid and that catches it. Flint, MI, water poisoning was detected by a kid on Medicaid.